diff --git a/ios/chrome/browser/web/model/choose_file/choose_file_tab_helper.mm b/ios/chrome/browser/web/model/choose_file/choose_file_tab_helper.mm
index 5ad4eb71d6a0e..8671a8a00fa07 100644
--- a/ios/chrome/browser/web/model/choose_file/choose_file_tab_helper.mm
+++ b/ios/chrome/browser/web/model/choose_file/choose_file_tab_helper.mm
@@ -231,11 +231,15 @@ void ChooseFileTabHelper::DidStartNavigation(
     web::NavigationContext* navigation_context) {
   if (!navigation_context->IsSameDocument()) {
     AbortSelection();
+    // Do not let a ChooseFileEvent posted by the previous document leak into
+    // the next document's RunOpenPanel call.
+    last_choose_file_event_.reset();
   }
 }
 
 void ChooseFileTabHelper::WasHidden(web::WebState* web_state) {
   AbortSelection();
+  last_choose_file_event_.reset();
 }
 
 void ChooseFileTabHelper::WebStateDestroyed(web::WebState* web_state) {