diff --git a/components/omnibox/browser/clipboard_provider.cc b/components/omnibox/browser/clipboard_provider.cc
index 3b6c952a88f8e..b4f4990f2e9d2 100644
--- a/components/omnibox/browser/clipboard_provider.cc
+++ b/components/omnibox/browser/clipboard_provider.cc
@@ -143,6 +143,14 @@ void ClipboardProvider::Start(const AutocompleteInput& input,
                               bool minimal_changes) {
   using OEP = ::metrics::OmniboxEventProto;
 
+  // Drop any in-flight UpdateClipboardMatchWithContent / image-encode callbacks
+  // before the controller publishes a new result set. Those callbacks bind a
+  // raw AutocompleteMatch* into AutocompleteController::published_result_,
+  // whose backing storage is freed by the next NotifyChanged().
+  // AutocompleteController::Start() does not call Stop() on providers, so this
+  // must be invalidated here as well as in Stop().
+  callback_weak_ptr_factory_.InvalidateWeakPtrs();
+
   matches_.clear();
 
   // If the user started typing, do not offer clipboard based match.