diff --git a/src/libANGLE/renderer/vulkan/vk_cache_utils.cpp b/src/libANGLE/renderer/vulkan/vk_cache_utils.cpp
index edee73da58..9d4e43b370 100644
--- a/src/libANGLE/renderer/vulkan/vk_cache_utils.cpp
+++ b/src/libANGLE/renderer/vulkan/vk_cache_utils.cpp
@@ -8652,16 +8652,13 @@ void SamplerCache::destroy(vk::Renderer *renderer, bool orphanReferencedSamplers
     {
         for (auto &iter : mPayload)
         {
-            // If the EGL_ANGLE_display_texture_share_group extension is causing some samplers to
-            // stay alive, stash them in the renderer to be destroyed when possible.
-            if (!iter.second.unique())
-            {
-                renderer->addSamplerToOrphanList(iter.second);
-            }
-            else
-            {
-                renderer->onDeallocateHandle(vk::HandleType::Sampler, 1);
-            }
+            // If the EGL_ANGLE_display_texture_share_group extension is in use,
+            // a "unique" sampler may still be referenced by an in-flight command
+            // buffer belonging to a different ShareGroup (the descriptor write
+            // copies only the raw VkSampler handle).  SamplerHelper carries no
+            // ResourceUse, so always defer destruction through the orphan list,
+            // which is gated on queue idle in cleanupOrphanedSamplers().
+            renderer->addSamplerToOrphanList(iter.second);
         }
     }
     else
diff --git a/src/libANGLE/renderer/vulkan/vk_renderer.cpp b/src/libANGLE/renderer/vulkan/vk_renderer.cpp
index 9fd124e604..49b9161d54 100644
--- a/src/libANGLE/renderer/vulkan/vk_renderer.cpp
+++ b/src/libANGLE/renderer/vulkan/vk_renderer.cpp
@@ -7477,6 +7477,15 @@ bool Renderer::cleanupOrphanedSamplers()
         return false;
     }
 
+    // SamplerHelper carries no ResourceUse, so we cannot know which in-flight
+    // command buffers still reference an orphaned sampler through a
+    // COMBINED_IMAGE_SAMPLER descriptor.  Conservatively defer destruction
+    // until the queue is idle (VUID-vkDestroySampler-sampler-01082).
+    if (mCommandQueue.isBusy(this))
+    {
+        return false;
+    }
+
     // Destroy any sampler that is no longer referenced.
     const size_t samplerCountBefore = mOrphanedSamplers.size();
     // Using remove_if to avoid unnecessary reference counter updates.